But when it comes to overall chemistry, Ryan and Hanks take home the trophy every time.

That’s largely because the two have cultivated a decades-long friendship off set (viaThe Things).

Here’s the truth about all that goes on between Meg Ryan and Tom Hanks behind the scenes.

Meg Ryan, Tom Hanks, You’ve Got Main premiere

He listens; he roots for other people (viaToday).

She also praised the fact that Hanks isn’t down with any on-set drama.

“We’re just really there to have fun,” she told Foster.

Meg Ryan smiling, red carpet

“This is supposed to be a creative experience and there’s no reason to get heavy.”

Ryan’s counterpart shares similar feelings about their ongoing collaboration.

“It was not like work.”

Tom Hanks posing on red carpet, wearing glasses

“I think that Tom informs all the other Toms,” she told the crowd.

Have Meg Ryan and Tom Hanks ever taken their love off screen?

Well, sorry to disappoint, but the pair have never dated in real life.

The happy couple is still going strong.

As far as Ryan’s love life is concerned, she married Dennis Quaid back in 1991.

It goes to show just how talented and close these two actors are they certainly had us fooled!